Phenotypes of gastroesophageal reflux disease: classification, pathogenesis and diagnostic criteria: A review
نویسندگان
چکیده
The literature review focuses on the current understanding of visceral hypersensitivity mechanisms in esophagus. Mechanisms peripheral and central sensitization their relation to heartburn symptoms are covered detail. Diagnostic criteria algorithms for non-erosive reflux disease, functional heartburn, esophagus based pH-impedance testing high-resolution esophageal manometry data presented.
منابع مشابه
Treatment of Gastroesophageal Reflux Disease - GERD | Clinical Review Criteria
Kaiser Permanente Clinical Review Criteria are developed to assist in administering plan benefits. These criteria neither offer medical advice nor guarantee coverage. Kaiser Permanente reserves the exclusive right to modify, revoke, suspend or change any or all of these Review Criteria, at Kaiser Permanente's sole discretion, at any time, with or without notice. Member contracts differ in their...
متن کامل[Diagnostic and treatment of gastroesophageal reflux disease].
We propose a diagnostic algorithm based on the evaluation of GERD symptoms, the test results with a single dose of alginate with heartburn and EGD--esophagogastroduodenoscopy data. The diagnosis of GERD with reflux esophagitis based on the endoscopic detection of characteristic changes of esophagus. Diagnostic criteria endoscopically negative forms of GERD are the presence of symptoms of concer...
متن کاملDiet and gastroesophageal reflux disease: role in pathogenesis and management.
PURPOSE OF REVIEW Gastroesophageal reflux disease (GERD) is a common disease that presents with a variety of symptoms including heartburn and acid regurgitation. Although dietary modification is currently regarded as first-line therapy for the disease, the role of diet in the pathogenesis and management of GERD is still poorly understood. The present article aims to review recent literature tha...
متن کاملGenetic factors in the pathogenesis of gastroesophageal reflux disease.
Multiple factors play a role in the pathogenesis of gastroesophageal reflux disease (GERD). Two landmark studies showing higher concordance of disease in monozygotic than dizygotic twin pairs suggested the role of host genetic factors in its pathogenesis. Recent studies have shown that genetic polymorphism in genes influencing host's inflammatory response, drug metabolism, cell cycle regulation...
متن کاملHelicobacter pylori infection in pathogenesis of gastroesophageal reflux disease.
Gastroesophageal reflux disease (GERD) refers to the very common and constantly increasing conditions where reflux of gastric contents into the esophagus leads to development of characteristic symptoms. The esophagus, LES and stomach can be envisioned as single functional unit controlled by neuro-hormonal factors. The abnormalities that contribute to GERD can start in any component of this unit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Consilium medicum
سال: 2022
ISSN: ['2075-1753', '2542-2170']
DOI: https://doi.org/10.26442/20751753.2022.5.201703